Is Nitric Oxide a Hormone?
Authors
Abstract:
Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this review is considering available literature on endocrine roles of NO and/or its metabolites, i.e. nitrite and nitrate. Existing data suggest the idea that NO is a hormone that after production in tissues, it is stabilized and transported as nitrite and/or S-nitrosothiols in the blood to target cells.
similar resources
is nitric oxide a hormone?
nitric oxide (no) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. recent evidences suggest that no may act as an endocrine molecule. the aim of this review is considering available literature on endocrine roles of no and/or its metabolites, i.e. nitrite and nitrate. existing data suggest the idea that no is a hormone that after production i...
full textIs nitric oxide a hormone?
Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this review is considering available literature on endocrine roles of NO and/or its metabolites, i.e. nitrite and nitrate. Existing data suggest the idea that NO is a hormone that after production i...
full textNitric Oxide is Protective Against Mercury Induced Depression
A B S T R A C T Introduction: Mercury is the second most metal pollutant in the world and has the potential to induce many pathologic conditions, especially in nervous system, such as depression. Here we tried to find out if nitric oxide has any possible role in the pathophysiology of depression induced by this metal. Although the role of nitric oxide has been shown in mood control, here we use...
full textBrain nitric oxide synthase is a haemoprotein.
Brain nitric oxide (NO) synthase showed pyridine haemochrome spectra typical of ferroprotoporphyrin IX-containing enzymes. The haem content of purified NO synthase was in the range 0.7-0.9 mol/mol of 160 kDa subunit. In the presence of CO, NO, KCN and miconazole, the L-citrulline-forming activity of NO synthase was markedly diminished, demonstrating that enzyme-bound haem is involved in enzymic...
full textnitric oxide is protective against mercury induced depression
a b s t r a c t introduction: mercury is the second most metal pollutant in the world and has the potential to induce many pathologic conditions, especially in nervous system, such as depression. here we tried to find out if nitric oxide has any possible role in the pathophysiology of depression induced by this metal. although the role of nitric oxide has been shown in mood control, here we use...
full textMitochondrial nitric oxide synthase, a voltage-dependent enzyme, is responsible for nitric oxide diffusion to cytosol.
The mitochondrial metabolic state regulates the rate of mitochondrial NO production and release to the cytosol. Nitric oxide release of rat heart mitochondria decreased markedly from 2.2 to 1.2 nmol NO/min. mg protein in the state 4 to state 3 transition. The activity of mtNOS, responsible for NO release, is driven by the membrane potential and not by intramitochondrial pH changes. The release ...
full textMy Resources
Journal title
volume 15 issue 3
pages 59- 65
publication date 2011-11
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023